Researchers identify enzyme that is an important regulator of aggressive...
Researchers at Cold Spring Harbor Laboratory (CSHL) have identified an enzyme that appears to be a significant regulator of breast cancer development. Called PTPN23, the enzyme is a member of a family...
View ArticleStudy: Statins may stem tumor growth
(Medical Xpress)—One of the world's top selling drugs potentially also acts against the growth of new lymphatic vessels, with potential implications for cancer therapy. This surprising finding was...
View ArticleScientists test new toxicant detection tool, links to abnormal fetal development
For more than 40 years, Bisphenol A, more commonly known as BPA, was used in everything from plastic baby bottles and the lining of metal food containers to dental sealants. When scientists began...
View ArticleProviding brain cells with the 3rd dimension to grow outside the body
Researchers at Sahlgrenska Academy in collaboration with Chalmers University of Technology developed a unique Bioactive3D culture system for brain cells. This system gives new possibilities to study...
View Article'Promiscuous parasites' hijack host immune cells
Toxoplasma gondii parasites can invade your bloodstream, break into your brain and prompt behavioral changes from recklessness to neuroticism. These highly contagious protozoa infect more than half the...
View ArticleCurrent chemical testing missing low-dosage effects of endocrine-disrupting...
Endocrine-disrupting chemicals (EDCs) -- such as BPA -- can show tangible effects on health endpoints at high dosage levels, yet those effects do not predict how EDCs will affect the endocrine system...
View ArticleScientists find promising vaccine targets on hepatitis C virus
A team led by scientists at The Scripps Research Institute has found antibodies that can prevent infection from widely differing strains of hepatitis C virus (HCV) in cell culture and animal models.
View ArticleHormone plays surprise role in fighting skin infections
Antimicrobial peptides (AMPs) are molecules produced in the skin to fend off infection-causing microbes. Vitamin D has been credited with a role in their production and in the body's overall immune...
View ArticleBoundary stops molecule right where it needs to be
A molecule responsible for the proper formation of a key portion of the nervous system finds its way to the proper place not because it is actively recruited, but instead because it can't go anywhere...
View ArticleNew proteins inhibit HIV infection in cell cultures
(Medical Xpress) -- Yale Cancer Center scientists have developed a new class of proteins that inhibit HIV infection in cell cultures and may open the way to new strategies for treating and preventing...
View ArticleIs Ovarian Cancer Linked to Ovulation?
(Medical Xpress) -- Could ovulation be the link to ovarian cancer? Joanna Burdette of the University of Illinois at Chicago College of Pharmacy thinks it might be, and she's working to find out.
View ArticleCertain mutations give HIV infection an advantage that sticks
(Medical Xpress)—Varieties of HIV that replicate more quickly can cause infected individuals' immune systems to decline faster, new research demonstrates. The results were published by the journal PLOS...
View ArticleNew study confirms immune cells are guided by gradients
(Medical Xpress)—A group of researchers in Austria and Switzerland has for the first time proven that immune cells migrate along chemical concentration gradients. This process has long been assumed but...
View ArticleExperimental molecular therapy crosses blood-brain barrier to treat...
Researchers have overcome a major challenge to treating brain diseases by engineering an experimental molecular therapy that crosses the blood-brain barrier to reverse neurological lysosomal storage...
View ArticleImaging fish in 3-D : Automated system for high-speed analysis of vertebrate...
Zebrafish larvae—tiny, transparent and fast-growing vertebrates—are widely used to study development and disease. However, visually examining the larvae for variations caused by drugs or genetic...
View ArticletPA: Clot buster and brain protector
(Medical Xpress)—Ever since its introduction in the 1990s, the "clot-busting" drug tPA has been considered a "double-edged sword" for people experiencing a stroke. It can help restore blood flow to the...
View ArticleAntibiotics: A new understanding of sulfonamide nervous system side effects
Since the discovery of Prontosil in 1932, sulfonamide antibiotics have been used to combat a wide spectrum of bacterial infections, from acne to chlamydia and pneumonia. However, their side effects can...
View ArticleStep toward a bioartificial liver device: A microreactor for hepatocyte cultures
Liver cells are very sensitive hence are difficult to cultivate outside the body. However, scientists from the Nałęcz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences...
View ArticleRed grapes, blueberries may enhance immune function
In an analysis of 446 compounds for their the ability to boost the innate immune system in humans, researchers in the Linus Pauling Institute at Oregon State University discovered just two that stood...
View ArticleResearch shows that anti-fungal medicine may increase vulnerability to...
Scientists at the University of Massachusetts Medical School (UMMS) and the Wellcome Trust Sanger Institute have discovered evidence that a widely used anti-fungal medicine increases susceptibility to...
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